CRLB-GMEL / About Us / History & Highlights
Our Journey

History & Highlights

From a single lipid research laboratory in 1977 to a world-class ISO-accredited biobank and genomics facility — the story of CRLB-GMEL.

A Timeline of Excellence

Our History

1977
Lipid & Lipoprotein Research Begins
Involvement in laboratory and clinical research of lipids, lipoproteins and apolipoproteins begins, examining their role in coronary heart disease risk assessment.
1987
CRLB Founded by Dr. Matthew McQueen
The Clinical Research and Testing Laboratory (CRCTL) — later renamed CRLB — is established at McMaster University to function as a central laboratory providing services for clinical trials.
1992
Dr. Salim Yusuf & PHRI Partnership
Dr. Salim Yusuf is recruited to McMaster University and establishes the Population Health Research Institute (PHRI), transforming the size and scope of the CRLB.
1990s
HOPE Study & Biobank Origins
CRLB becomes actively involved in large peer-reviewed studies beginning with the HOPE Study — 9,000+ participants from 28 countries. Samples moved to nitrogen vapour storage at −160°C to −180°C for long-term stability.
2010
GMEL Established Under Dr. Guillaume Paré
The Genetic & Molecular Epidemiology Laboratory (GMEL) is established as a collaboration between McMaster, PHRI, and TaARI under Dr. Guillaume Paré, focusing on genetic testing and cardiovascular genomics.
2014
IQMH ISO 15189 Plus Accreditation
The laboratory and biobank receives IQMH ISO 15189 Plus accreditation — the gold standard for medical laboratory quality management.
2020
CRLB + GMEL Merge to Form CRLB-GMEL
The CRLB and GMEL combine under a unified identity with Dr. Guillaume Paré as Director and Dr. Matthew McQueen as Deputy Director.
2023+
Olink Certified Service Provider
CRLB-GMEL becomes one of only four Canadian labs — and one of two offering the full Olink spectrum — to be certified as an Olink service provider, establishing the lab as an international leader in proteomics.
In partnership with
Hamilton Health Sciences
Population Health Research Institute
McMaster University