ISO 15189 Plus  ·  Est. 1987  ·  Hamilton, Canada

Research at every scale.
Quality without compromise.

From exploratory pilot studies to landmark multinational clinical trials spanning 85+ countries, CRLB-GMEL delivers ISO-accredited biobanking, biomarker, proteomic and genomic services with uncompromising quality.

0M+
Aliquots of blood and urine in Canada’s largest research biobank
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Source countries · 100+ PHRI studies supported
0K+
Specimens shipped annually
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Nearly four decades of research excellence
Biobanking Biomarker Analysis Proteomics Genomics Metabolomics Bioinformatics
Our Unique Advantage

Built for Any Scale of Study

We are uniquely positioned to serve the complete spectrum of research — from a first feasibility study to a multi-decade global cohort — with the same expert team and ISO-accredited rigour at every scale.

Landmark Global Trials

Decades of experience managing specimens from 85+ countries. Our infrastructure has supported some of the most cited clinical trials in cardiovascular and population health research.

HOPE · PURE · ON-TARGET · RE-LY · ACCORD · ORIGIN

Small Studies & Pilot Research

The same ISO-accredited standards, the same expert team, the same publication-quality data — available to investigator-led studies, pilot projects, and academic research collaborations of any size.

Pilot Studies · Feasibility Projects · Academic Collaborations · Basic Research
Capabilities

Full-Spectrum Laboratory Services

End-to-end support for the entire research lifecycle — delivering data publishable in top-tier international journals.

Biobanking

4,000,000+ aliquots of blood and urine in nitrogen vapour at −160°C to −180°C — the largest research biobank in Canada.

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Biochemistry & Biomarkers

From single-plex ELISA to high-throughput automated analysis on Roche, Siemens, Beckman Coulter, Abbott and Bio-Rad platforms.

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Proteomics

Olink®, SomaScan® and Alamar NULISA® — 3,000+ proteins per sample, from focused panels to proteome-wide discovery.

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Genomics

Two genotyping platforms, DNA sequencing, gene expression and DNA methylation — 10 million genetic variants per DNA sample.

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Metabolomics

Metabolomic analysis alongside genomic and proteomic data for multi-omics study designs.

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Bioinformatics

Study design, quality control, statistics and reporting — 200+ terabytes of data processed.

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Collaboration History

A Legacy of Landmark Research

Our history spans some of the most influential cardiovascular, diabetes, and population health studies ever conducted.

HOPEHOPE-3INTERHEARTPUREON-TARGETTRANSCENDRE-LYACCORDORIGININTERSTROKEDREAMEpiDREAMPRoFESSCURRENTACTIVEAVERROESPOISEOASIS-5OASIS-6CLSASHARECUREASPIREBristol-Myers SquibbMerck-Frosst CanadaAstraZenecaSandoz CanadaFournier PharmaMerck Banyu Japan
In Partnership With
Hamilton Health Sciences
Population Health Research Institute
McMaster University

Ready to Discuss Your Study?

Whether you’re planning a global trial or a focused pilot — our team is ready to help at any scale.

Contact Our Team →